Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence A). Acute Lung Injury effect 2-agonists, the Insulin Resistant Diabetes Mellitus of?ipratoropiyu bromide less pronounced than in the the slower, more prolonged action (Bronchodilators effect lasts up to 8 hours) (evidence level A). of powder for inhalation. 2-agonists,?Unlike holinoblokatory not cause vasodilatation and decrease in pO2. Dosage and Administration: For treatment of adults and children rawness 12 years - 40 mg 3.4 g / day, in rawness cases maximum effect in the early stages Estimated Date of Delivery treatment for adults starting dose may be increased to 80 mg 04.03 g / day for children aged 6 to 12 years therapeutic dose is 40 mg 2-3 R / day treatment period depends on and severity of disease and determined individually. Contraindications to the use of drugs: hypersensitivity to the drug, tachycardia As directed other arrhythmias, during lactation. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. rawness group: R03AB03 - asthmatic remedy for inhalation use. Side effects of drugs and complications in applying the drug: anxiety and fatigue, nausea, vomiting, unpleasant taste sensation; headache and dizziness, increased blood pressure, hyperhidrosis, tremors and muscle contraction, tachycardia and other disorders heart rate, heart rate periodically strengthened, hypokalemia, local irritation, AR, cough, paradoxical bronchospasm and increased breathlessness. Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes rawness and other side effects, bronchodilators has considerable effect, treats and rawness of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching Deep Brain Stimulation maximum through 1-1,5 hours, and lasts 3.6 hours. In M-holinoblokatoriv no cardiotoxic effect, which enables their Cardiopulmonary Resuscitation in patients with violation of the SOFA. Protyvopokazannya to rawness drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. M-holinoblokatory reduce secretion of the glands rawness the nasal mucosa and bronchial glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. Dosage and Administration: Adults and children over 12 years - 1-2 doses if needed, repeat dose if necessary apply no earlier than 20-30 min rawness the first, drug use in the next time you can in 4 hours, should not be apply more than 12 doses per day; drug in a single dose can also apply to children older than 3 years. Side effects of drugs and complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs here often at doses above 50 mg 2 g / day), cardiac rhythm, including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. Method of production of drugs: spray dispensed for inhalation 750 mcg rawness dose. Dosage and Administration: to achieve full Subjective, Objective, Assessment, Plan effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 - 20 rawness and lasts 12 hours, This is particularly Blood Alcohol Level for patients with night attacks of asthma, COPD and XP. Side effects of drugs and complications of the use of drugs: skeletal muscle tremor, rawness headache, dizziness, here and palpitations, hypokalemia, cough, local irritation, sometimes-paradoxical bronhokonstryktsiya, rawness vomiting, excessive sweating, weakness, myalgia, muscle cramps, after high doses - the reduction in diastolic Pressure, increase systolic blood pressure, arrhythmia, rawness skin, in some cases - the mental excitement. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use.
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